Nasal spray that treats Erectile Dysfunction in 5 minutes due in 2025
Health experts say they are developing a nasal spray Viagra that could be available as early as 2025. The nasal spray could treat erectile dysfunction up to 10 times faster than Viagra.
While Viagra was revolutionary when it hit shelves in the 1990s, but experts say it takes up to an hour to act, potentially ruining a spur-of-the-moment sexual encounter. The new experimental nasal spray treatment named Spontan, triggered an erection in as little as five minutes in early trials and could be available in the next two years.
Lee Rodne, who heads up the Australian company developing the spray, suggested it could be the most significant advancement in helping men keep an erection since Viagra emerged.
Millions of men in Nigeria suffer from erectile dysfunction, or the inability to get or maintain an erection during sexual activity. When a man gets an erection, the smooth muscles around the penis relax, allowing blood to flow into the region. In those with erectile dysfunction, this system may be disrupted by heart disease or emotional issues such as stress and anxiety limiting blood flow to the penis.
When aroused, the increase in blood flow allows a man to have a stronger erection. The drug must be taken orally and takes 30 minutes to an hour to kick in because it is absorbed by the digestive system.
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But doctors at Brisbane-based bio company LTR Pharma are now working on the spray drug that will use vardenafil, sold under the brand name Levitra. It is different from Viagra, which uses the drug sildenafil.
The treatment works faster than standard Viagra because it is absorbed directly into the bloodstream via the nose. Early proof-of-concept studies in California showed the treatment acted within five to 15 minutes. It is now moving into larger trials in Australia, which will start recruiting men in the second half of this year.
These trials are expected to start reporting results in the first half of next year. If successful, the company says it will apply to the Food and Drug Administration for approval of its drug. This is expected by 2025.
Lee Rodne, the executive chairman of LTR Pharma, said: “Our nasal delivery bypasses the digestive system so it really goes straight into the bloodstream and had an effect in five to 15 minutes.
“We expect it to be a lot more effective than oral tablets so that it works consistently and in a quicker and faster amount of time, so men don’t have to plan ahead and they don’t have variable results. We have very high confidence in the drug. This product has already had a small proof-of-concept clinical study in California that showed a fast-acting rapid onset effect.”
Erectile dysfunction (ED) is a very common clinical problem and can contribute to relationship breakdowns and mental health issues. It’s estimated the condition will affect around 40 percent of men, with the prevalence increasing with age.
Viagra works by relaxing the muscle cells in blood vessels supplying the penis, allowing more blood to flow into it. The drug also thins the blood making it flow more easily.
The drug, which has been manufactured by Pfizer since it first hit the market in 1998, was initially for older men dealing with erectile dysfunction.
While the drug has been approved by the Food and Drug Administration (FDA) and deemed okay for proper use by regulators, like all drugs, it can be dangerous if misused.
It can cause priapism, where a person has an erection that lasts for hours and causes permanent damage to the penis. It also has a few dangerous interactions with drugs for high cholesterol.
Vanguard
5 reasons men need to eat pineapple before sexual intercourse
Sex ought to be an enjoyable activity, but many factors can get in the way of such enjoyment. Factors like low libido, lack of stamina, and erections can prevent such enjoyment. That’s why pineapples are so important. Many people believe it only benefits women, but it has many sexual benefits for men.
Pineapples are rich in manganese, an antioxidant that fights free radicals and prevents cellular damage. A manganese deficiency can lead to diseases like heart disease and diabetes, which are linked to erectile dysfunction. However, adequate manganese intake can increase blood flow and prevent infertility.
Pineapples are rich in bromelain, which increases testosterone production and provides many sexual benefits in bed. This hormone regulates libido and encourages nitric oxide oxidation which makes men more sexually active.
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Pineapples are also rich in vitamin C and thiamine which can increase low libido in men. Thiamine stimulates the development of sex hormones, and this is especially important when men can’t have an erection during sex.
Pineapple can help increase sexual stamina, especially for those who find themselves exhausted from sex. Sex requires endurance and stamina, with studies showing men can burn up to 101 calories in 30 minutes of sex. To enjoy bedroom fun without exercising, consider indulging in pineapples, which are rich in vitamins B1 and C, which can help increase sexual stamina.
Pineapple consumption before sex can enhance the taste of ejaculate by making it sweeter. This is due to the high levels of acid and sugar in pineapple, which make semen less bitter and more sweet. The primary benefit for partners is the added sweetness, in case they want to taste it.
Raw pineapple, rich in vitamin C, is an antioxidant that strengthens the immune system and prevents inflammation. Studies on rats have linked reduced inflammation to improved blood flow, which is important for sexual health.
This is because healthy blood flow is essential for achieving sexual arousal and erectile function for penetrative sex. This increased blood flow and higher blood pressure within the penis make the penis firm and erect.
Finally, a cup of pineapple or one pineapple finely chopped is enough; do not eat more than that, as it will have the opposite effect.
NAFDAC alerts to counterfeit Tandak injection in Nigeria
The National Drug Law Enforcement Agency (NAFDAC) has alerted Nigerians about the sale of counterfeit TANDAK injection 1.5g powder and water for injection, manufactured by Intracin Pharmaceuticals PVT. LTD C-1, B-53, G.I.D.C Estate, Nadiad- 387001, Gujarat, India.
A statement released by the agency on Wednesday, April 10, says the counterfeit product was discovered in Gombe State, Nigeria, and reported to the Agency by Marcson Healthcare Ltd. – the Marketing Authorisation Holder (MAH).
‘’Tandak® injection of 1.5g powder is a co-formulation of Ceftriaxone 1000mg and Sulbactam 500mg. It is prescribed for use in the treatment of various types of bacterial infections. It fights against micro organisms by preventing their growth, and further spread of the infection. Ceftriaxone+Sulbactam 1000mg/500mg Injection should only be administered under the supervision of a healthcare professional. the statement read
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The illegal marketing of counterfeit medicines poses a risk to the health of people, since by not complying with the regulatory provisions, the safety, quality, and efficacy of the products are not guaranteed.
NAFDAC has directed all its Zonal Directors and State Coordinators to carry out surveillance and mop up the counterfeit products within the Zones and States.
Healthcare professionals and consumers are advised to report any suspicion of the sale of substandard and falsified medicines or medical devices to the nearest NAFDAC office, call 0800-162-3322 or send an email to sf.alert@nafdac.gov.ng.
NAFDAC recalls Benylin cough syrup
The National Agency for Food and Drugs Administration and Control has recalled Benylin Paediatrics Syrup manufactured by Johnson & Johnson, following recent toxicity findings in the laboratory on the product.
NAFDAC said laboratory analysis conducted on the product showed that it contains an unacceptable high level of Diethylene glycol and was found to cause acute oral toxicity in laboratory animals.
The agency disclosed this on its website on Wednesday.
A product recall is an important method of managing risks in response to product safety events and emergencies.
According to an online health portal, Science Direct, a product recall is a request to return to the maker, a batch, or an entire production run of a product, usually over safety concerns, design defects, or labelling errors.
“Benylin Paediatric syrup is indicated for the relief of cough and its congestive symptoms and for the treatment of hay fever and other allergic conditions in children aged two to 12 years.
“Diethylene glycol is toxic to humans when consumed and can prove fatal. Toxic effects can include abdominal pain, vomiting, diarrhea, inability to pass urine, headache, altered mental state, and acute kidney injury which may lead to death,” it noted.
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The details of the product showed that the product is manufactured by Johnson & Johnson in Cape Town, South Africa.
With batch number 329304, the product was manufactured in May 2021, and it is to expire this month, April 2024.
NAFDAC, however, implored importers, distributors, retailers, and consumers to exercise caution and vigilance within the supply chain to avoid the importation, distribution, sale, and use of substandard (contaminated) regulated products.
It said all medical products must be obtained from authorised/licensed suppliers. The products’ authenticity and physical condition should be carefully checked.
“Anyone in possession of the above-mentioned product is advised to immediately discontinue the sale or use and submit stock to the nearest NAFDAC office. If you witness any adverse reaction/event after the use of this product in any children, you are advised to direct such patients to immediate medical attention from a qualified healthcare professional.
“Healthcare professionals and consumers are advised to report any suspicion of substandard and falsified medicines to the nearest NAFDAC office, NAFDAC on 0800-162-3322 or via email: sf.alert@nafdac.gov.ng
“Similarly, healthcare professionals and patients are also encouraged to report adverse events or side effects related to the use of the medicinal product to the nearest NAFDAC office, or through the use of the E-reporting platforms available on the NAFDAC website www.nafdac.gov.ng or via the Med-safety application available for download on android and IOS stores or via e-mail on pharmacovigilance@nafdac.gov.ng,” it added.
Meanwhile, the agency said it has directed the marketing authorisation holder (Johnson and Johnson company, West Africa) to initiate the recall of the batch and the notice will also be uploaded to the WHO Global Surveillance and Monitoring System.
NAFDAC regulates and controls the manufacture, importation, exportation, distribution, advertisement, sale, and use of food, drugs, cosmetics, medical devices, packaged water, chemicals, and detergents.
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