Health

WHO Steps Up Ebola Response, Prioritises Vaccine Testing Amid Outbreak

Published

3 months ago

May 29, 2026

WHO Steps Up Ebola Response, Prioritises Vaccine Testing Amid Outbreak

The World Health Organisation (WHO) has intensified global efforts to contain the ongoing outbreak of Ebola disease caused by the Bundibugyo virus, convening top scientific and advisory groups to urgently evaluate experimental vaccines and therapeutics as cases continue to emerge in the Democratic Republic of the Congo (DRC), with additional cross-border infections reported in Uganda.

The latest outbreak has raised fresh concerns among international health authorities because the Bundibugyo ebolavirus is one of the less common species of Ebola virus, and currently has no licensed vaccine or approved therapeutic treatment, unlike the more common Zaire ebolavirus for which approved countermeasures exist.

In a statement released after a high-level emergency consultation, WHO said its expert advisory groups concluded that all promising medical countermeasures for Bundibugyo virus disease (BVD) should only be deployed within carefully designed clinical trials to ensure scientific evidence generation while maintaining strict safety and ethical standards. (who.int)

The organisation disclosed that the review involved its R&D Blueprint Technical Advisory Group, the Strategic Advisory Group of Experts on Immunisation (SAGE), and WHO’s Ebola Vaccine Working Group, which assessed all available vaccine and treatment candidates for immediate deployment feasibility.

WHO said the current outbreak underscores a major research gap in global preparedness for non-Zaire Ebola strains, particularly the Bundibugyo species, which caused significant outbreaks in Uganda in 2007 and the DRC in 2012, with fatality rates ranging between 25 and 50 per cent, according to historical outbreak data. (cdc.gov)

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For treatment of confirmed infections, independent experts prioritised three investigational therapeutics for immediate clinical trial evaluation.

These include the monoclonal antibody MBP134, Maftivimab®, and the antiviral drug remdesivir, all of which have shown potential antiviral activity against filoviruses in preclinical and limited clinical settings.

The advisory groups also endorsed testing combination therapy involving a monoclonal antibody and remdesivir to determine whether combined treatment could improve survival outcomes.

WHO stressed that none of these interventions should be administered outside structured clinical protocols.

For post-exposure prophylaxis among individuals who have had direct contact with confirmed or probable cases, experts identified the oral antiviral obeldesivir as a priority candidate.

The strategy involves rapidly administering oral tablets to exposed contacts to assess whether infection can be prevented before symptom onset.

However, WHO warned that this approach depends heavily on rapid case detection and effective contact tracing, both of which remain operational challenges in some affected communities due to security concerns and difficult terrain.

On vaccines, WHO identified the single-dose rVSV Bundibugyo vaccine, developed by the International AIDS Vaccine Initiative (IAVI), as the most promising candidate for future trial deployment.

The vaccine is estimated to require seven to nine months before becoming trial-ready.

A second candidate, ChAdOx1 Bundibugyo, developed by the University of Oxford in collaboration with the Serum Institute of India, could be available for efficacy trials within two to three months, pending additional animal safety and immunogenicity data.

Experts said a single-dose vaccination strategy could be suitable for immediate ring vaccination of contacts of infected persons, while a two-dose regimen may be more appropriate for frontline health workers and other high-risk responders.

The panels also reviewed Ervebo, currently the world’s only licensed Ebola vaccine.

Although Ervebo has proven highly effective against Zaire ebolavirus, WHO said there is currently no conclusive evidence that it offers protection against the Bundibugyo strain.

As a result, the organisation advised that Ervebo should not be used outside rigorously controlled research settings specifically designed to evaluate possible cross-protection.

WHO said it is collaborating closely with the governments of the DRC and Uganda, the Africa Centres for Disease Control and Prevention (Africa CDC), the French National Agency for Research on AIDS and Viral Hepatitis (ANRS), and other global partners to fast-track ethical clinical trial protocols.

The organisation emphasised that all research activities must meet the highest international ethical standards, with affected communities actively involved in decision-making and national authorities maintaining oversight.

WHO also called for accelerated deployment of essential laboratory supplies, stronger surveillance systems, enhanced community engagement, and coordinated international funding to support rapid evaluation of Bundibugyo-specific countermeasures.

Despite the accelerated research push, WHO reiterated that the immediate priority remains containing transmission through established Ebola control measures, including rapid diagnosis, case isolation, contact tracing, infection prevention and control, community education, safe burials, and intensive surveillance.

Health officials warned that while scientific progress offers hope, effective outbreak containment will depend primarily on swift public health action and strong regional cooperation.

WHO Steps Up Ebola Response, Prioritises Vaccine Testing Amid Outbreak

Health

Kano diphtheria outbreak: Over 50 children reportedly dead as lawmakers demand urgent action

Published

3 days ago

August 25, 2026

Trends Admin

Kano diphtheria outbreak: Over 50 children reportedly dead as lawmakers demand urgent action

The Kano State House of Assembly has called on Governor Abba Kabir Yusuf to urgently intervene in a reported diphtheria outbreak in Rano Local Government Area, where lawmakers say more than 50 children have died.

The alarm was raised during Monday’s plenary after the member representing Rano Constituency, Ibrahim Muhammad, presented a motion of urgent public importance before the House, presided over by Speaker Ismail Falgore.

Muhammad said the outbreak had particularly affected communities in Ridin and Sabuwar Kaura, where more than 50 children were reportedly killed by the disease.

He said emergency measures had already been initiated, including the purchase of medication and deployment of health workers to the affected communities. However, the lawmaker stressed that the response needed to be significantly strengthened to contain the outbreak and prevent additional deaths.

Muhammad appealed to Governor Yusuf and the Kano State Commissioner for Health to provide further emergency assistance to the affected communities, warning that the disease had spread extensively in the area.

He also expressed concern over the recurrence of the outbreak, noting that a similar incident had reportedly claimed several lives in the area last year.

The situation, according to another lawmaker, has also raised concerns beyond Rano. Supporting the motion, the member representing Kiru Constituency, Usman Abubakar Tasiu, said the outbreak had reportedly spread to communities in Kiru, including Kwarin Dangora, Dangora town and Yelwa.

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Tasiu disclosed that an APC youth leader in Kiru reportedly lost two children to the disease within one day. He called for the establishment of an emergency committee to coordinate the response across affected local government areas.

He proposed that the emergency response should cover Rano, Tudun Wada, Kibiya, Bunkure, Bebeji and Kiru, amid concerns that transmission could spread further without stronger intervention.

Another lawmaker, Saleh Ahmad, representing Dawakin Tofa Constituency, urged the state government to intensify vaccination and other preventive measures. He warned that diphtheria is contagious and can spread rapidly to neighbouring communities.

The Majority Leader of the House, Lawan Husseini, also urged the state government to invoke the provisions of the state’s Health Protection Law to contain the outbreak.

According to Husseini, the law empowers the government to provide emergency relief and free healthcare while allowing authorities to isolate affected persons and restrict movement where necessary in areas affected by infectious diseases.

The Assembly subsequently approved the motion and directed its Committee on Health to engage the Ministry of Health on the implementation of the law and the provision of emergency relief to affected communities.

The latest development is particularly concerning because Kano has historically carried a large share of Nigeria’s diphtheria burden. Previous health surveillance data showed that Kano recorded thousands of suspected and confirmed cases during Nigeria’s prolonged diphtheria outbreak, alongside hundreds of deaths.

Diphtheria is a serious bacterial infection that can cause severe illness and death, particularly among people who are unvaccinated or inadequately vaccinated. The disease can spread through respiratory droplets and close contact, making rapid detection, treatment, contact tracing and vaccination important components of outbreak control.

The reported deaths in the current Rano outbreak are based on statements made by Kano lawmakers. The specific death toll should therefore be treated as reported by the Kano State House of Assembly pending further confirmation from relevant health authorities.

The lawmakers’ intervention puts additional pressure on the state government to verify the scale of the current outbreak, strengthen disease surveillance, provide medicines and other emergency supplies, intensify vaccination and ensure that affected residents have timely access to treatment.

The immediate priority is to prevent further deaths and stop the reported spread of the disease from Rano to neighbouring communities.

Kano diphtheria outbreak: Over 50 children reportedly dead as lawmakers demand urgent action

Health

FG strengthens emergency response, releases medical hotlines for Nigerians

Published

1 week ago

August 20, 2026

Trends Admin

FG strengthens emergency response, releases medical hotlines for Nigerians

The Federal Government has urged Nigerians to dial 112 whenever they face a medical emergency requiring urgent attention, as it released a list of emergency medical call centre numbers covering states across the country and the Federal Capital Territory (FCT).

The National Emergency Medical Service and Ambulance System (NEMSAS) said the toll-free 112 emergency number serves as a central access point for emergency medical assistance, while several states have additional dedicated numbers to facilitate faster responses.

NEMSAS said its emergency response system is designed to provide rapid intervention, professional medical care and life-saving services, with emergency responders available around the clock.

The agency released emergency contact numbers covering 35 states and the FCT, although it listed the emergency call centres in Benue and Imo as not operational.

Under the emergency contact arrangements, residents of Abia can call 112 or 08000000800, while those in Adamawa can use 112, 1755 or 07011111443.

In Akwa Ibom, the listed numbers are 112, 08000022322 and 08000022422, while residents of Anambra can call 112, 5111 or 08002200008.

Residents of Bauchi can dial 112 or 07038636433, while Bayelsa residents can use 112 or 08002200223. NEMSAS listed Borno as 112 or 08000000033, while Cross River has 112 as its listed emergency number.

For Delta, the listed contacts are 112, 07041008130 and 07041008131, while residents of Ebonyi can call 112, 08086446891 or 08086445736.

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In Edo, residents can use 112, 739 or 09037999871, while Ekiti lists 112, 08000606606, 0811111122, 0811111133, 0811111144 and 0811111155.

Residents of Enugu can call 112, 09074996090 or 07066466429, while Gombe lists 112 or 07033825646. Jigawa has 112 as its listed emergency number, while Kaduna residents can call 112 or 08064111599.

For Kano, the listed emergency contacts are 112, 09019999920 and 09049999914. Katsina and Kebbi each have 112 listed as their emergency number.

Residents of Kogi can dial 112, while Kwara residents can call 112, 09062010001 or 09062010002.

In Lagos, the listed emergency numbers are 112 and 767, while Nasarawa residents can use 112 or 08144911269.

Residents of Niger State can call 112, 08022422953 or 08155577513, while those in Osun can use 112, 08111110532 or 08111110561.

For Ogun, the listed numbers are 112 and 08112000033, while Ondo residents can call 112 or 08055300300.

Residents of Oyo can dial 112 or 615, while Plateau lists 112 or 09136982496.

In Rivers, residents can call 112, 09040222281, 09040222283 or 09040222285, while Sokoto residents can use 112, 07045963318 or 07071765080.

For Taraba, the listed emergency contacts are 112, 07041122777 and 07041100777, while Yobe residents can call 112, 09169981792 or 08000090009.

Zamfara has 112 as its listed emergency number, while residents of the FCT can call 112, 09157892931 or 09157892932.

The release is part of ongoing efforts by the Federal Government to strengthen emergency medical services in Nigeria, improve ambulance response and reduce delays in transporting patients to appropriate healthcare facilities.

NEMSAS has previously disclosed that emergency medical service structures have been established across the 36 states and the FCT, although the level of operational readiness differs from one state to another.

The agency has also identified challenges affecting the nationwide use of 112, including connectivity problems and inadequate public awareness. It has called for stronger collaboration with telecommunications providers to improve access to the emergency line.

To complement the national number, NEMSAS has therefore encouraged states to maintain dedicated emergency call centres and provide alternative contacts for residents.

The Federal Government is also pursuing a digital emergency dispatch platform designed to connect emergency callers, ambulance operators and healthcare facilities. The system is expected to support faster dispatch, patient tracking, referrals and coordination between emergency responders and treatment centres.

NEMSAS has expanded the deployment of emergency response assets, including ambulances and other vehicles designed to reach communities that may be difficult to access with conventional emergency vehicles.

The agency’s Rural Emergency Service and Maternal Transport (RESMAT) programme is also aimed at improving access to emergency transportation for pregnant women, newborns and other residents in underserved communities.

NEMSAS has called for greater public awareness of emergency services and urged Nigerians not to delay seeking help when confronted with life-threatening situations.

The agency advised residents to save 112 and their relevant state emergency numbers on their mobile phones so they can quickly request assistance when needed.

NEMSAS stressed that its emergency medical response service operates 24 hours a day, seven days a week, and that prompt access to professional emergency care can be critical in saving lives.

FG strengthens emergency response, releases medical hotlines for Nigerians

Health

Stage 4 Cancer: Understanding Ogogo’s Diagnosis and Treatment Options

Published

1 week ago

August 18, 2026

Trends Admin

Veteran Yoruba actor Taiwo Hassan, popularly known as Ogogo

Stage 4 Cancer: Understanding Ogogo’s Diagnosis and Treatment Options

The recent emotional appeals by the daughters of veteran Yoruba actor Taiwo Hassan, popularly known as Ogogo, have drawn national attention to the realities of stage-four cancer. The 66-year-old film icon’s family revealed he was diagnosed with the advanced disease about three weeks ago and that hospitals have indicated they can no longer continue chemotherapy. This has sparked confusion and concern, prompting a medical expert to clarify what a stage-four diagnosis truly means, how it is treated, and why palliative care is not the same as being abandoned.

Stage-four cancer is the most advanced stage in the commonly used TNM staging system. It generally means the cancer has spread from where it first developed to distant parts of the body—a process known as metastasis. Dr. Olusina Ajidahun, a medical doctor and health communicator known as The Bearded Dr Sina on X, explained it simply: “Stage 4 cancer means the cancer has left the primary organ and gone to other sites.” Cancer staging uses the TNM system to assess the size and extent of the main tumor, whether nearby lymph nodes are affected, and whether the cancer has spread to distant parts of the body. The stage given at diagnosis remains the same, even if the cancer worsens or spreads further.

Symptoms of cancer vary depending on the type and location of the disease. According to medical experts, possible symptoms include unexplained weight loss, persistent tiredness, unusual bleeding, persistent pain, a lump or swelling anywhere on the body, changes in bowel or bladder habits, persistent cough or hoarseness, difficulty swallowing, and changes to the skin. For metastatic cancer, symptoms depend on where the cancer has spread. Spread to the bones can cause pain or fractures, spread to the brain can cause headaches, seizures, or dizziness, spread to the lungs can cause shortness of breath, and spread to the liver can cause jaundice or abdominal swelling. It is important to note that many of these symptoms can be caused by other illnesses, and a persistent or unusual symptom should always be assessed by a healthcare professional rather than self-diagnosed. Some cancers may cause few or no noticeable symptoms in their early stages, which is why regular screenings are recommended for certain cancers and groups of people. Early diagnosis can significantly improve the chances that cancer will respond to treatment.

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Yes, stage-four cancer can be treated. Treatment depends on several factors, including the type of cancer, where it has spread, the characteristics of the cancer, the patient’s general health, and how the cancer responds to treatment. Depending on the circumstances, doctors may use chemotherapy, immunotherapy, targeted therapy, hormone therapy, radiation therapy, or surgery. In October 2025, Nigeria launched its first immunotherapy program for metastatic colorectal cancer at National Hospital Abuja, marking a significant step forward in advanced cancer care in Sub-Saharan Africa. For many patients with metastatic cancer, the goals of treatment shift to shrinking or controlling the cancer, slowing its growth, relieving symptoms, helping the patient live longer, and maintaining quality of life. Research shows advancements in treatment options are helping people with metastatic cancer live longer and have a better quality of life overall.

Dr. Ajidahun clarified that when patients reach stage four and chemotherapy and other available therapies have been explored, doctors may recommend palliative care. “When patients have stage 4 cancer and chemo and/or other therapies have been explored, there is a form of care called PALLIATIVE CARE… which is end-of-life care and care for terminal diseases because at the point of the disease you cannot treat it, but you can manage associated symptoms and give the person a good quality of life before death,” he explained. He stressed that moving a patient to palliative care does not mean medical treatment has been withdrawn. Rather, it may reflect a change in the goal of care, particularly when doctors believe further aggressive treatment could cause more harm than benefit. Palliative care focuses on improving quality of life, managing symptoms such as pain, difficulty breathing, and other problems associated with cancer or its treatment. It does not necessarily mean that cancer treatment has stopped or that doctors have given up on the patient.

Dr. Ajidahun cautioned that describing the situation as hospitals refusing to treat the actor could create a misleading impression and potentially expose medical personnel to hostility. “Saying they don’t want to treat my father makes it look like they are intentionally rejecting him, and in the context of recent happenings in the health sector, it can trigger an insurrection and put a bad label on health care workers,” he said. In response to one of Ogogo’s daughters mentioning herbs as a possible option, Dr. Ajidahun issued a strong warning: “There are no herbs that will treat a stage 4 cancer.” He cautioned that unverified concoctions could damage more organs and cause further complications, ultimately wasting money and creating more problems. “These concoctions will end up damaging more organs and causing more complications. You’d end up wasting money and causing more problems,” he said.

Public information about Ogogo’s health remains limited. His daughters have publicly said that he is battling stage-four cancer and have appealed for medical assistance. According to reports, several hospitals have turned their father away because of his condition, and the family is seeking medical direction rather than financial donations. The public reports do not establish the specific type of cancer Ogogo has, the extent to which it may have spread, or his detailed medical prognosis. Those questions can only be properly assessed by his medical team after reviewing his diagnosis, scans, pathology results, treatment history, and overall health. Key takeaways from this explanation are that stage-four cancer means the cancer has spread to distant parts of the body, treatment is still possible and may aim to control the cancer, relieve symptoms, and prolong life, palliative care focuses on managing symptoms and improving quality of life and is not abandonment, herbal remedies for stage-four cancer are dangerous and unproven, and Ogogo’s specific prognosis cannot be determined from public information alone.