Health
NAFDAC withdraws approval of major anti-malaria drug

NAFDAC withdraws approval of major anti-malaria drug
The National Agency for Food and Drug Administration and Control (NAFDAC) has officially stopped the registration of Artemether/Lumefantrine dry powder for oral suspension, a widely used multi-dose anti-malarial medication.
The agency announced this decision through Public Alert No. 01/2025, posted on its website Thursday, citing concerns about the product’s stability after reconstitution, which may compromise its effectiveness.
According to the alert, “stability studies have shown that once reconstituted, the Artemether/Lumefantrine oral suspension becomes unstable, which can result in a loss of efficacy.”
This suspension covers both locally manufactured and imported versions of the product. NAFDAC stated it would no longer process new registrations, renewals, or variation applications for the drug.
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The agency warned that the instability of the suspension could lead to severe health consequences, including “worsening health conditions, increased risks of complications, treatment delays, or even death.”
In response, NAFDAC has instructed its zonal directors and state coordinators to conduct surveillance operations and remove the affected products from circulation.
The agency urged healthcare professionals, distributors, and retailers to halt the importation, sale, and distribution of the product immediately. Consumers and medical practitioners have also been encouraged to report any sightings of the drug or instances of substandard or counterfeit medicines to the nearest NAFDAC office.
Reports of adverse reactions or side effects can also be submitted via NAFDAC’s E-reporting platforms or through the Med-safety app, available on both Android and iOS devices.
NAFDAC confirmed that this alert would be shared with the World Health Organisation’s Global Surveillance and Monitoring System (GSMS).
NAFDAC withdraws approval of major anti-malaria drug
Health
Loneliness kills over 871,000 people annually – WHO

Loneliness kills over 871,000 people annually – WHO
No fewer than 871,000 people die worldwide annually from loneliness, the World Health Organisation (WHO) revealed on Monday.
According to the WHO commission, one in every six persons globally suffers from loneliness, which, combined with social isolation, can lead to physical sickness.
It claimed that loneliness raises the risk of strokes, heart attacks, diabetes, depression, anxiety, and suicide.
According to the World Health Organisation, lonely teenagers are 22% more likely to get lower grades than their peers, and lonely adults have more difficulty finding or retaining a job.
The impact is societal as well as individual, with billions of dollars in healthcare bills and job losses.
Vivek Murthy, the commission’s co-chair, defines loneliness as “a painful, subjective feeling that many of us experience when the relationships that we need do not match the relationships that we have.
“And social isolation, by contrast, is an objective state of having few relationships or interactions.”
The survey estimates that one in every three elderly individuals and one in every four adolescents are socially isolated.
Its reasons include disease, inadequate education, low money, a lack of opportunity for social connection, living alone, and the usage of digital technologies.
Murthy observed that humans have communicated for millennia using not only words but also facial expressions, body language, tone of voice, and silence.
When people rely primarily on cell phones and social media, they lose touch with traditional modes of communication.
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The WHO cited Sweden as a positive example. Swedish Social Minister Jakob Forssmed said that the country has adopted a national strategy to combat loneliness.
Sweden believes that loneliness is a societal problem rather than an individual one.
Efforts are being made to develop social ties in shops, restaurants, neighbourhoods, and clubs.
Soon, all children and teenagers in Sweden will be given prepaid cards that can only be used to book group recreational activities.
According to Forssmed, Sweden aims to ban mobile phones in public schools.
According to studies, this improves social interaction while decreasing cyberbullying.
Children and teenagers sleep better and find it simpler to put their phones away during leisure time.
Forssmed said that youngsters are frequently frustrated when their parents are continually preoccupied by their phones.
While digital technology brings benefits, such as permitting previously unthinkable video calls.
The commission stressed the necessity of providing spaces in life where people can communicate face-to-face without being distracted by technology.
Murthy said, “Having places and spaces in our lives where we can interact face-to-face with other people without the distraction of technology is very important.”
Loneliness kills over 871,000 people annually – WHO
Health
Revolution in fertility: AI uncovers sperm missed by labs, enables IVF success

Revolution in fertility: AI uncovers sperm missed by labs, enables IVF success
A revolutionary breakthrough in fertility treatment has given new hope to couples struggling with male infertility. Scientists at Columbia University Fertility Center in the United States have used artificial intelligence (AI) to detect viable sperm in a man previously diagnosed with azoospermia, a condition marked by an extremely low or non-existent sperm count.
The couple had been trying to conceive for 18 years without success. But in March 2025, the woman became pregnant after receiving an embryo fertilised with sperm identified through the cutting-edge AI system.
From Zero to Forty-Four: AI Sees What Labs Couldn’t
According to Dr Zev Williams, lead researcher and director of the fertility programme, traditional laboratory methods failed to detect any sperm even after two days of examination. But the AI-powered system located 44 viable sperm cells in under an hour.
“Labs searched for two days and found nothing. We ran the same sample and found 44 sperm within an hour,” Williams said. “That changes everything for a couple who thought they had no path forward.”
How the STAR System Works
The system, called Sperm Track and Recovery (STAR), combines advanced AI with a fluidic chip. As the semen sample flows through a tiny plastic tubule, a high-speed camera captures millions of microscopic images. The AI software, trained to spot viable sperm, scans these images in real time flagging healthy cells that would otherwise be missed.
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Once detected, the sperm can be frozen or used in intracytoplasmic sperm injection (ICSI), an IVF method where a single sperm is injected directly into an egg.
This approach reduces the need for painful and invasive surgical sperm retrieval, offering a far less traumatic option for men diagnosed with azoospermia.
Experts React: “It Could Be Life-Changing”
The innovation has sparked excitement across the medical community. Dr Robert Brannigan, president-elect of the American Society for Reproductive Medicine, described the breakthrough as “promising.”
“Even the discovery of a single viable sperm can be life-changing,” he said.
Dr Allison Rodgers, a fertility specialist in Illinois, added, “It’s amazing and shows that what we thought was advanced still has a long way to go. I believe AI is going to absolutely revolutionise IVF.”
However, not everyone is ready to celebrate just yet. Dr Gianpiero Palermo of Weill Cornell Medicine urged caution, warning that the technology still needs further validation.
“You are attracting patients who have been told they have no sperm and offering what may turn out to be false hope,” he said.
What’s Next for AI in Fertility?
Dr Williams and his team are now working on expanding the technology’s capabilities to identify not just healthy sperm, but also viable eggs and embryos potentially transforming the future of reproductive medicine.
Revolution in fertility: AI uncovers sperm missed by labs, enables IVF success
Health
Nightmares triple risk of early death, says new study

Nightmares triple risk of early death, says new study
A disturbing new study out of the UK has revealed a hidden killer lurking in dreams. If you suffer from regular nightmares, you could be three times more likely to be dead a decade earlier than the average person, the new study has suggested.
Weekly nightmares were also found to be a stronger indicator of an early death than smoking, obesity, poor diet, and little physical activity. Children and adults with frequent nightmares also showed faster biological ageing, which accounted for approximately 40 per cent of the explanation for the increased risk of early death.
From the study, even monthly nightmares were linked to faster ageing and increased mortality, compared to those who rarely or never have them.
Researchers from Imperial College London and the Dementia Research Institute say experiencing frequent nightmares may be an ominous signal of premature death—tripling the risk of dying before age 70.
The research found that weekly nightmares were more strongly linked to early death than well-known culprits like tobacco use, poor diet, and lack of exercise. Adults and children who frequently experienced nightmares also showed signs of accelerated biological ageing—suggesting that the worst dreams may wear people down on a cellular level.
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Dr Abidemi Otaiku, the lead investigator, explained that nightmares provoke intense stress reactions that mimic life-threatening situations.
“Our brains don’t always know the difference between a nightmare and reality. They trigger real physiological responses—elevated heart rate, sweating, and adrenaline—that can take a toll night after night,” Otaiku said.
Involving data from over 185,000 people tracked over 19 years, the study is the first to link the frequency of bad dreams with long-term mortality. Adults reporting at least one nightmare per week were three times more likely to die early. Children weren’t spared either: those with frequent night terrors also showed faster biological decline.
According to the study, even monthly nightmares carried risk. Compared to those with peaceful sleep, occasional bad dreamers still showed signs of biological stress and reduced lifespan. The impact, researchers said, appears tied to poor sleep quality and chronic spikes in the stress hormone cortisol.
But hope isn’t lost. Experts recommend lifestyle changes like cutting down on watching horror movies, practising stress management, and improving sleep hygiene. Therapies such as Image Rehearsal Therapy—in which individuals rewrite the endings of their nightmares—and Cognitive Behavioural Therapy for Insomnia (CBT-I) have shown promising results in reducing both bad dreams and their long-term health effects.
Nightmares triple risk of early death, says new study
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